Irregular pops are introduced with desktop Safari 16.4 For Samples: https://g200kg.github.io/webaudio-tinysynth/simple.html This player that does not belong to me, yet I am having same type of pops with my own applications. You can click and hover around the keys to have the pops appear faster. For Osc: http://mmckegg.github.io/web-audio-school/ Same pops can be heard with this simple patch in a rare manner. Sometimes in 1st go, sometimes in 5th. If computer is connected to an external sound card (Apogee Ensemble Thunderbolt in my case), clicks are even more regular as in each play with multiple pops. Switching between sound cards and reloading pages yields consistent results. Regular pops with external sound card, less regular pops with internal sound card. Both examples work fine with other browsers and iOS Safari.